I got MU3E just because I love the setting, but the rules have ALWAYS fallen flat for me. I recently did a conversion from MC3E to Savage Worlds, and myself an a group of friends played 3-sessions with the Savaged Mutant Chronicles, and I have to say, it went smoother with Savage Worlds. I can only imagine trying to learn the 2d20 system and then trying to teach it to my players! GURPS is one of the best systems I've seen for an RPG, so, I've been working on a GURPS 4th ed Mutant Chronicles adaptation. If you'd like to see what OI've got so far, head over to: [http://gurps.wikia.com/wiki/Mutant_Chronicles] and take a look.